Key Health Benefits

Use Case	Summary of Findings	PubMed Link
Antioxidant Enzyme (Cu/Zn SOD)	Copper is a critical cofactor for Cu/Zn-superoxide dismutase (SOD). For example, in malnourished infants, copper supplementation significantly increased red blood cell SOD activity (from 1,073 to 1,371 U/g Hb, restoring it to normal levels).	PubMed
Iron Metabolism & Anemia	Copper is required for iron transport and red blood cell formation. Copper deficiency can cause anemia, which is reversible with supplementation – e.g. in copper-deficient patients, oral copper (such as copper gluconate) raised hemoglobin from ~6.8 to 9.9 g/dL within months, correcting the anemia.	PubMed
Immune System Function	Adequate copper is vital for immune cells (lymphocytes, neutrophils, macrophages). In one trial, a very low-copper diet significantly reduced T-lymphocyte proliferation in healthy men, while restoring copper intake partially improved these immune responses. Copper deficiency is also known to cause neutropenia (low neutrophil count) that reverses with copper repletion.	PubMed
Collagen/Elastin & Connective Tissue	Copper is essential for collagen and elastin cross-linking via the enzyme lysyl oxidase. In copper deficiency, lysyl oxidase activity fails, leading to weak connective tissue, while giving copper to deficient animals increases lysyl oxidase and enables normal collagen/elastin maturation. Thus, copper supplementation supports healthy connective tissue (skin, blood vessels, etc.).	PubMed

Dosage Recommendation

Goal	Capsules per Day
General Maintenance	1 capsule daily (providing 2 mg elemental copper from gluconate)
Immune & Antioxidant Support	1–2 capsules daily with meals (up to 4 mg/day total)
Connective Tissue Health	2 capsules daily, preferably with vitamin C and collagen-supporting nutrients
Bone & Mineral Support	1–2 capsules daily alongside calcium, magnesium, and vitamin D3
Anemia Prevention (at-risk)	2 capsules daily in conjunction with iron-support formulas (under professional guidance)

Supplement Facts

NUTRITIONAL INFORMATION
Serving Size: 2 veg. Capsule
	Amt. per Serving	% RDA Men	% RDA Women
Elemental Copper	1700 mcg	100	100
Green Tea Extract(40%)	500 mg	**	**
Ingredients: Green Tea Extract(40%)(Camellia sinensis-green tea extract), Copper(as Copper Gluconate),6 Bulking Agent INS 460 (i), Anticaking Agent (INS 341(iii)) & Vegetable Capsule Shell (HPMC) (INS 464)

When Will I See Results?

Goal	Expected Timeline
Antioxidant Enzyme Activity	1–2 weeks for increased Cu/Zn-SOD activity in blood samples
Iron Mobilization	3–4 weeks for improvements in serum ferritin and hemoglobin levels
Immune Function	4–6 weeks for enhanced neutrophil and lymphocyte activity
Skin & Connective Tissue	6–8 weeks for better wound healing and skin elasticity
Bone Mineralization	8–12 weeks to observe changes in bone density markers (e.g., via DXA or bone turnover markers)

How to Maximize Results

Goal	Synergistic Stack / Habit
Antioxidant Defense	Copper + Zinc (10 mg) + Selenium (55 µg) to support SOD and glutathione peroxidase
Connective Tissue	Copper + Vitamin C (500 mg) + Collagen peptides to enhance collagen cross-linking
Bone & Mineral Support	Copper + Calcium + Magnesium + Vitamin D3 for balanced mineralization
Immune Health	Copper + Vitamin A (beta-carotene) + Vitamin D3 to support innate and adaptive immunity
Iron Metabolism	Copper + Iron (15–30 mg) + Vitamin C to facilitate iron absorption and transport

What to Avoid

Substance / Condition	Why to Avoid	Advice
Excess Zinc (>50 mg/day)	High zinc doses can compete with copper absorption, leading to deficiency	Maintain Zn:Cu ratio of ~10:1; space zinc supplements by 2 hrs
High-Dose Iron Alone	Free iron can generate oxidative stress if not balanced by copper-dependent antioxidants	Supplement iron with copper and antioxidants like vitamin C
Phytic Acid-Rich Foods	Phytates (in grains, legumes) can chelate copper, reducing its bioavailability	Soak/sprout grains & legumes; space high-phytate meals away from dosing
Excessive Vitamin C (>2 g/day)	Very high vitamin C may increase copper excretion	Keep vitamin C ≤1 g/day when focusing on copper retention
Medications Affecting Absorption	Antacids and proton pump inhibitors can impair mineral absorption including copper	Take copper at least 2 hrs apart from acid-blocking drugs

Third Party NABL Lab Report

Third Party NABL Lab Report for Copper Gluconate :

 

Click here to view the report