Key Health Benefits

Benefit	Description	PubMed Link
Platelet support (Dengue)	Carica papaya leaf extract significantly increases platelet counts in dengue patients. In a controlled trial, dengue patients treated with papaya leaf extract saw platelet counts rise by ~482% by day 3 (vs. 331% on placebo) and reached >50,000/µL one day sooner. Treated patients also showed reduced IL-6 inflammation and faster viral NS1 clearance.	PubMed
Immune modulation & Antiviral	Papaya leaf is rich in compounds that modulate innate and adaptive immunity. A recent review highlights its antiviral activity not only against dengue but also other viruses (COVID-19, HIV, Zika). The leaf’s bioactives enhance host immune response while reducing inflammation and oxidative stress, thereby inhibiting viral replication.	PubMed
Digestive health	Papaya leaf preparations support digestion and relieve functional gut disorders. In a double-blind trial of a papaya extract (Caricol®), patients with chronic indigestion/IBS reported significant improvement in constipation and bloating compared to placebo. The study concluded that papaya preparation helps maintain normal gastrointestinal function in such disorders.	PubMed
Liver protection & detoxification	Papaya leaf shows hepatoprotective properties in preclinical and review reports. Its antioxidant constituents (flavonoids, vitamins) help protect liver cells from toxic damage. This suggests a role in liver detoxification and protection against chemically-induced hepatic injury (though human trials on liver endpoints are limited).	PubMed
Antioxidant & Anti-inflammatory	The leaves are rich in antioxidants and exhibit anti-inflammatory effects. In dengue patients, papaya leaf extract significantly reduced IL-6 (an inflammatory cytokine) compared to placebo. Overall, reviews note the high free-radical scavenging capacity and inflammation-modulating activity of papaya leaf extract.	PubMed

Dosage Recommendation

Goal	Stack
Increase Platelet Count	1,000 mg papaya leaf extract daily (divided doses)
Immune & Antiviral Support	500 mg papaya leaf extract twice daily
Antioxidant & Inflammatory Relief	500 mg papaya leaf extract twice daily with meals
Digestive Health & Enzyme Support	500 mg papaya leaf extract before meals
Liver Detox & Protection	500–1,000 mg papaya extract daily

Supplement Facts

NUTRITIONAL INFORMATION
Serving Size: 1 veg. Capsule
	Amt. per Serving	% RDA Men	% RDA Women
Papaya Leaf Extract	500mg	**	**
Ingredients: Papaya Leaf Extract (Carcia Papaya), Bulking Agent INS 460 (i), Anticaking Agent (INS 341(iii)) & Vegetable Capsule Shell (HPMC) (INS 464)

More Details

About this item

• HealthyHey Nutrition Papaya Leaf Extract - 500mg/serving - 60 vegetable capsules
• Supports in maintaining Blood Platelet Count
• Antioxidant
• Supports immune Health

 

 

Ingredients:

Papaya Leaf Extract

When Will I See Results?

Goal	Expected Timeline
Platelet Count Recovery	2 – 5 days for initial platelet increase (as seen in dengue and thrombocytopenia studies)
Immune & Antiviral Defense	1 – 2 weeks for reduced incidence of illness and improved immune activity
Anti-Inflammatory Effects	2 – 4 weeks for reduced inflammation markers and oxidative stress
Digestive Support	3 – 7 days for relief from bloating, constipation, or indigestion symptoms
Liver Enzyme Balance	2 – 4 weeks for measurable reductions in AST, ALT, and improvement in liver function tests (if mildly elevated)

How to Maximise Results

Goal	Stack & Lifestyle Tips
Platelet Count Support	• Combine with vitamin C and maintain hydration• Avoid NSAIDs, aspirin, and alcohol which can suppress platelet function
Immune Defense	• Stack with zinc and echinacea• Practice good hygiene, sleep 7–8 hrs, and avoid overtraining during viral outbreaks
Digestive Comfort	• Take before meals• Include dietary fiber and fermented foods• Avoid excess sugar, fried foods, and carbonated beverages
Liver Health & Detox	• Add NAC or milk thistle extract• Avoid alcohol, high-fat processed foods• Increase intake of cruciferous vegetables (e.g., broccoli, kale)

What to Avoid

Substance / Habit	Reason to Avoid	Spacing Tip
High-dose use (>1,500 mg/day long-term)	Excessive doses may lead to GI upset, hepatotoxicity, or interact with certain medications	Stick to recommended dose or under medical supervision
Pregnancy & Breastfeeding	Papaya (especially unripe or concentrated extracts) may stimulate uterine contractions or affect fetal development	Avoid unless prescribed by a healthcare provider
Concurrent Use with Anticoagulants	Papaya may influence clotting mechanisms, especially in high doses	Use caution with warfarin or aspirin; consult physician
Taking on Empty Stomach (if sensitive)	May cause mild stomach irritation in sensitive individuals	Take with food or light snack
Severe Allergies to Latex or Papain	Papaya contains latex-related enzymes (papain) which may cause allergic reactions in latex-sensitive individuals	Discontinue use if any signs of hypersensitivity appear

Third Party NABL Lab Report

Third Party NABL Lab Report for Papaya Leaf Extract :

 

Click here to view the report