Key Health Benefits

Use Case	Summary	PubMed Link
Nitric oxide & blood flow enhancement	In older men, 14 days of L-citrulline (6 g/day) increased femoral artery blood flow by ~11% during exercise (with higher plasma L-arginine), demonstrating enhanced NO-mediated circulation.	PubMed
Exercise performance & endurance	In trained cyclists, one week of L-citrulline (2.4 g/day) significantly improved 4-km cycling time trial performance by ~1.5% and raised plasma L-arginine versus placebo, indicating enhanced endurance.	PubMed
Muscle soreness reduction & recovery	A placebo-controlled trial in men found that 8 g of citrulline malate taken pre-exercise reduced muscle soreness by ~40% at 24–48 hours post-exercise compared to placebo, suggesting faster recovery.	PubMed
Ammonia clearance & fatigue resistance	In a mouse study of intense exercise, citrulline supplementation increased time to exhaustion and blunted the exercise-induced rise in blood ammonia and lactate, indicating improved ammonia clearance and reduced fatigue.	PubMed
Cardiovascular support (BP & endothelial function)	In hypertensive postmenopausal women, 4 weeks of L-citrulline (10 g/day) improved endothelial function (↑brachial artery FMD) and significantly lowered aortic blood pressure (diastolic BP and mean arterial pressure) vs. placebo.	PubMed

Dosage Recommendation

Goal	Servings per Day
Performance & Endurance	1 scoop (2 g) mixed in water 30–60 min before training
Muscle Recovery & Soreness	1 scoop (2 g) immediately post-workout and again 12 h later (total 16 g split into two doses)
General NO & Blood Flow Support	½ scoop (1 g) daily, preferably before exercise or throughout the day divided into two 4 g doses
Fatigue Resistance	1 scoop (2 g) pre-exercise to enhance ammonia clearance and delay fatigue
Cardiovascular Health	1 scoop (2 g) daily with a meal for 4 weeks to support blood pressure reduction and endothelial function

Supplement Facts

NUTRITIONAL INFORMATION
Serving Size: 1 veg. Capsule
	Amt. per Serving	% RDA Men	% RDA Women
L-Citrulline DL-Malate	2g	**	**
Ingredients: L-Citrulline DL-Malate 2:1 & Anticaking Agent INS 551

When Will I See Results?

Outcome	Expected Timeline
Enhanced Blood Flow	Within 1 hour post-dose, vasodilation and perfusion improvements
Performance Gains	Noticeable immediately in power output and repetition endurance
Reduced Soreness	24–48 hours post-exercise for reduced muscle soreness
Fatigue Delay	Within a single session, delayed onset of fatigue observed
Blood Pressure Lowering	2–4 weeks of daily dosing for measurable systolic BP reduction

How to Maximize Results

Goal	Synergistic Stack & Habits
NO & Blood Flow	Citrulline Malate + Beetroot Juice (nitrate source) + Vitamin C
Strength & Power	Citrulline Malate + Creatine Monohydrate + Beta-Alanine
Recovery & Soreness	Citrulline Malate + BCAAs + Omega-3 (EPA/DHA)
Fatigue Resistance	Citrulline Malate + Sodium Bicarbonate (buffering agent) + Adequate hydration
Cardiovascular Health	Citrulline Malate + Magnesium + Regular aerobic exercise

What to Avoid

Substance / Condition	Why to Avoid	Advice
High-Protein Meals (pre-dose)	Protein-rich foods can blunt citrulline absorption via shared transporters	Take on an empty stomach or at least 1 h before/after meals
Stimulants (e.g., caffeine)	May exacerbate vasodilatory effects, leading to jitters or tachycardia	Monitor total stimulant intake; adjust dosage if needed
Antihypertensive Medications	Additive blood pressure–lowering effects could cause hypotension	Consult your healthcare provider when combining
Excessive Sodium Bicarbonate	Can cause GI discomfort when combined in high doses	Use moderate buffering protocols; split doses
Dehydration	Impairs nutrient delivery and performance	Maintain ≥2 L water daily, more around workouts

Third Party NABL Lab Report

Third Party NABL Lab Report for Citrulline Malate :

 

Click here to view the report