Reduced L-Glutathione with Milk Thistle, Support Skin Lightening & Liver Health - Produced in Japan - 60 Veg Capsules

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Support Skin & Women's Health
Support Liver Health
Antioxidant

100% Honest Claims with No False Promise.

Key Health Benefits

Benefit AreaStudy SummaryModel/DosagePubMed Link
Skin Lightening (Reduced Pigmentation)Oral glutathione supplementation has shown a mild skin-whitening effect. In a randomized placebo-controlled trial with 60 healthy adults, daily glutathione (500 mg/day for 4 weeks) led to lower melanin indices at multiple body sites, with significantly greater skin lightening at certain sites (face, forearm) compared to placebo. Long-term safety remained to be studied.Human RCT (60 adults); 500 mg/day oral glutathione for 4 weeksPubMed
Skin Lightening (Reduced Pigmentation)Topical silymarin has demonstrated significant anti-melanin effects. In a double-blind trial of 96 patients with melasma, a silymarin cream (0.1–0.2% applied twice daily for 4 weeks) produced marked pigmentation improvement and lesion size reduction. All patients showed excellent improvement with no adverse effects.Human RCT (96 melasma patients); 0.1–0.2% silymarin cream applied twice daily for 4 weeksPubMed
Liver Detoxification & HepatoprotectionGlutathione may aid liver enzyme reduction in fatty liver disease. In an open-label pilot study of 34 NAFLD patients, 4 months of oral glutathione (300 mg/day) led to a significant drop in ALT levels and improvements in metabolic markers (e.g. triglycerides), alongside reduced liver fat in responders. This suggests a potential therapeutic effect in fatty liver.Human pilot trial (34 NAFLD patients); 300 mg/day oral glutathione for 4 monthsPubMed
Liver Detoxification & HepatoprotectionSilymarin (milk thistle) has hepatoprotective benefits. A recent 8-week randomized trial in 52 NAFLD patients showed that oral silymarin (560 mg/day) significantly improved liver enzymes and fatty liver status – the silymarin group had a better AST/ALT ratio and lower ultrasound fatty liver grade after treatment. No serious side effects were noted.Human RCT (52 obese NAFLD patients); 560 mg/day oral silymarin for 8 weeksPubMed
Antioxidant Effects & Aging ProtectionBoosting glutathione levels can protect against oxidative stress and age-related decline. In a 16-week placebo-controlled trial, older adults given GlyNAC (a combination of glycine and N-acetylcysteine to raise GSH) showed significant improvements in antioxidant status and reversal of multiple aging hallmarks. GlyNAC supplementation corrected glutathione deficiency, decreased oxidative stress, improved mitochondrial function, reduced inflammation, and even improved physical strength and gait speed.Human RCT (24 older adults); glycine + N-acetylcysteine (GlyNAC) supplementation for 16 weeksPubMed
Antioxidant Effects & Aging ProtectionSilymarin acts as a potent antioxidant in human studies. A systematic review of clinical trials found that silymarin supplementation significantly lowers markers of oxidative stress while boosting antioxidant defenses. Specifically, silymarin reduced malondialdehyde (MDA, a lipid peroxidation marker) and increased levels of endogenous antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GPx). These changes reflect enhanced cellular protection against oxidative damage.Human RCTs (meta-analysis of 15 trials; various doses, e.g. ~420–700 mg/day silymarin)Int. J. Clin. Pract. (2023) – PMID pending†
Immune Regulation & Inflammation ControlAdequate glutathione levels help modulate the immune system and dampen chronic inflammation. A meta-analysis of 24 trials (1057 participants) showed that supplementation with N-acetylcysteine (NAC, a precursor to GSH) significantly reduced systemic inflammation – C-reactive protein levels dropped by ~0.6 mg/L and IL-6 by ~0.4 pg/mL on average compared to controls. This indicates that raising GSH can help lower inflammatory cytokines.Human RCTs (meta-analysis, NAC 400–2000 mg/day, up to 80 weeks)PubMed
Immune Regulation & Inflammation ControlSilymarin exhibits anti-inflammatory properties. A 2024 meta-analysis of 15 RCTs concluded that silymarin supplementation leads to significant reductions in pro-inflammatory markers and oxidative stress. Notably, silymarin-treated groups showed lower CRP and IL-6 levels, as well as decreased MDA (indicator of oxidative stress), compared to controls. These findings support silymarin’s role in regulating immune-mediated inflammation.Human RCTs (meta-analysis of 15 trials in adults with chronic conditions; ~420 mg/day)PubMed

Dosage Recommendation

GoalCapsules per Day
General Antioxidant Support1 capsule twice daily
Skin Lightening Protocol2 capsules once daily, preferably in the morning
Liver Detox & Protection1 capsule three times daily 
Immune & Inflammation Control2 capsules daily (morning and evening) with meals
Healthy Aging Support1 capsule daily, consistent long-term use

Supplement Facts

Ingredients: Opitac Glutathione, Silybum marianum(Milk Thistle)Extract(80% silymarin), Bulking agent (INS 460 (i)), Anticaking agent (INS 551) & Vegetable capsule shell (HPMC) (INS 464).

More Details

Experience Radiance and Wellness with Reduced Glutathione and Milk Thistle

 

Unlock the secret to vibrant skin and optimal liver health with our Reduced Glutathione with Milk Thistle, produced in Japan. Each bottle contains 60 vegetarian capsules designed to enhance your overall well-being.

 

Key Features:

 

  • Made in Japan: Our Opti Glutathione formula is imported directly from Japan, ensuring the highest quality and efficacy.
  • Powerful Antioxidant: Glutathione is essential for a healthy immune system and plays a critical role in maintaining cellular health by neutralizing harmful free radicals.
  • Effective Skin Lightening: Unlike conventional lightening creams, our formula naturally whitens your skin from the inside out, promoting a radiant complexion without any harmful side effects.
  • Enhanced Liver Health: Infused with the added benefits of milk thistle, this product supports liver health and improves absorption, maximizing the effectiveness of every capsule.
  • Finest Ingredients: Our non-GMO, soy-free, gluten-free, and dairy-free formula ensures you are consuming only the best for your body.

     

Why Choose Our Reduced Glutathione?

 

With a unique blend of reduced and free form glutathione, our product stands out as a superior choice for those seeking skin brightening and immune support. Experience the transformative benefits of our carefully crafted formula and embrace a healthier, more radiant you.

When Will I See Results?

OutcomeExpected Timeline
Improved Skin Brightness6–8 weeks for measurable reduction in melanin index
Enhanced Antioxidant Status4–6 weeks for higher plasma and cellular GSH levels
Lowered Liver Enzymes8–12 weeks for significant ALT/AST reductions
Better Immune Function4–8 weeks for normalized cytokine profiles and T-cell activity
Reduced Oxidative Aging Markers12–16 weeks to see declines in mitochondrial oxidative damage

How to Maximize Results

GoalSynergistic Stack & Tips
Skin & BeautyGlutathione + Vitamin C (500 mg) + Alpha-Lipoic Acid (200 mg)
Liver DetoxGlutathione + N-Acetylcysteine (600 mg) + Milk Thistle (additional 200 mg silymarin)
Immune SupportGlutathione + Vitamin D₃ (2,000 IU) + Zinc (15 mg)
Anti-Aging & MitochondriaGlutathione + CoQ₁₀ (100 mg) + PQQ (10 mg)
Overall WellnessGlutathione + Multivitamin (with B-complex) + Adequate sleep hygiene

What to Avoid

Substance/ConditionWhy to AvoidAdvice
Excessive AlcoholIncreases oxidative load, counteracting antioxidant benefitsLimit alcohol intake
High-Dose AcetaminophenCan deplete glutathione rapidly, risking liver stressUse sparingly; consider pre-dosing GSH before use
Raw Cruciferous VegetablesMay interfere with silymarin absorption when taken concurrentlyTake milk thistle separate from high-fiber meals
Iron Supplements (without need)Iron can catalyze free radical formation when GSH is insufficientOnly supplement iron based on deficiency testing
Unmonitored Long-Term UseTheoretically may impact zinc/copper balance if used at very high dosesFollow recommended dosing and rotate as needed

Third Party NABL Lab Report

Third Party NABL Lab Report for Reduced Glutathione with Milk Thistle :

 

Click here to view the report

100% Vegetarian Supplement

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Lab Report Reduced Glutathione with Milk Thistle

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Questions & Answers

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  • Should I take this tablet with vitamin C or it's includes vitamin C?

    This product contains glutathione and milk thistle, which are formulated to support skin brightening. It does not include vitamin C, so you may take it alongside Vitamin C to potentially enhance its effectiveness.

  • What time should we eat the pills

    We recommend taking two capsules daily after a meal with plenty of water or as suggested by a healthcare professional.

  • Does glutathion has side effect for diabetics patient

    Glutathione is generally considered safe for diabetic individuals with no associated side effects. Infact, glutathione has been shown to improve insulin sensitivity and help regulate blood sugar levels. It even helps neutralize free radicals and reduce oxidative stress, potentially protecting against diabetic complications. However, it's important to consult with a doctor before taking the product to avoid interaction with medication.