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TMG trimethylglycine with Vitamin B12 - 60 vegetable capsules
Regular price
Rs. 809.00
inc. of GST
Regular price
-43%
Rs. 1,419.00
Sale price
Rs. 809.00
inc. of GST
Support Homocysteine levels
Support Liver Health
Improve Performance
Science-Backed, 100% Honest Claims with No False Promises.
Key Health Benefits
| Benefit | Description | PubMed Link |
|---|---|---|
| Homocysteine reduction | TMG (betaine) provides methyl groups (via the BHMT enzyme) to convert homocysteine into methionine, markedly lowering plasma homocysteine. In healthy adults, a meta‐analysis found ≥4 g/day betaine lowers homocysteine by ~1.2 μmol/L. In a controlled trial, combining 4 g TMG with folate and B12 reduced homocysteine by ~24%. This demonstrates that TMG (with B12) effectively supports one-carbon metabolism to clear homocysteine. | PMID: 31408467 |
| Cardiovascular support | By lowering homocysteine, TMG/B12 may reduce atherosclerotic risk. In fact, reviews note betaine “improves vascular risk factors” (e.g. liver and vascular health) via methylation. However, several trials found high-dose TMG raises LDL and total cholesterol, which could offset benefits. Thus, while TMG+B12 improves homocysteine‐driven CV risk, its net effect on lipids is mixed. | PMID: 15916468 |
| Methylation & detox support | TMG is a key methyl donor in the liver/kidneys, maintaining S-adenosylmethionine (SAM) and preventing hypomethylation. It remethylates homocysteine to methionine (via BHMT), supporting normal methylation in cells. Adequate methylation is critical for detox pathways and gene regulation; insufficient methyl donors cause elevated Hcy and fatty liver. Thus, TMG+B12 supplementation helps preserve healthy methylation status and clearance of toxic metabolites. | PMID: 15321791 |
| Enhanced exercise performance | TMG has ergogenic effects on muscle performance. Human trials show betaine supplementation boosts strength and power. For example, 14 weeks of 2 g/day betaine increased athletes’ 1‑RM strength, VO₂max and sprint ability. Similarly, 6 weeks of 5 g/day betaine improved upper-body power and half-squat strength. These findings indicate TMG (+ B12 co-factors) can enhance endurance and power output in trained individuals. | PMID: 34663363 |
| Mood & cognitive enhancement | TMG’s methyl donation supports brain methylation and SAMe synthesis. Elevated homocysteine is linked to cognitive decline, so TMG’s Hcy-lowering can be neuroprotective. Clinically, TMG has shown antidepressant synergy: one trial found SAMe + betaine improved depression more than SAMe alone. By aiding neurotransmitter methylation (with B12 and folate), TMG may thus enhance mood and cognitive resilience. | PMID: 25678811 |
Dosage Recommendation
| Goal | Stack |
|---|---|
| Methylation & Detox Support | Stack TMG capsule with milk thistle extract for liver phase II detox enzyme activity. |
| Cardiovascular Health | Combine with Omega-3 to reduce endothelial inflammation and support heart health |
| Exercise Performance & Recovery | Take TMG pre-workout; optionally combine with creatine monohydrate for enhanced strength and ATP support. |
Supplement Facts
NUTRITIONAL INFORMATION | |||
| Serving Size: 1 veg. Capsule | |||
| Amt. per Serving | % RDA Men | % RDA Women | |
| Betaine (Trimethylglycine) | 600mg | ** | ** |
| Vitamin B12 | 2.2mcg | 100 | 100 |
| Ingredients: Betaine (Trimethylglycine), Bulking Agent INS 460 (i), Anticaking Agent (INS 341(iii)), Vitamin B12 & Vegetable Capsule Shell (HPMC) (INS 464) | |||
More Details
Support homocysteine Levels
Support Liver Health
- HealthyHey Nutrition TMG trimethylglycine with Vitamin B12 - 600mg/serving - 60 vegetable capsules
- Support Homocysteine Levels
- Support Liver Health
- Manufactured at FSSAI, FSSC-22000, ISO-22000, GMP & USFDA registered Facility at Mumbai
Ingredients:
TMG trimethylglycine with Vitamin B12
When Will I See Results?
| Goal | Expected Timeline |
|---|---|
| Homocysteine & Methylation Support | 2 – 4 weeks for measurable reduction in homocysteine and improvement in methylation cycle efficiency |
| Detoxification & Liver Health | 2 – 6 weeks for improved liver enzyme levels and detox biomarkers |
| Cardiovascular Markers | 4 – 8 weeks for reduced arterial stiffness, homocysteine, and improved lipid-associated inflammation |
| Performance Enhancement | 1 – 2 weeks for improved power output and reduced fatigue (especially with doses ≥ 2 g/day) |
| Mood & Neurological Function | 2 – 4 weeks for better mood, motivation, and reduction in fatigue, especially in B12-deficient individuals |
How to Maximise Results
| Goal | Stack & Lifestyle Tips |
|---|---|
| Homocysteine Control | Take TMG with B12 and methylated folate (5-MTHF)Include leafy greens, beans, and fish in dietReduce alcohol, which impairs methylation |
| Exercise Recovery | Pair with protein (20–30 g) and electrolytesStay well hydratedUse post-training to reduce soreness and support muscle integrity |
| Mood & Cognitive Function | Ensure adequate sleep (7–8 hrs/night)Combine with adaptogens (e.g., Rhodiola) if under chronic stressAddress any B-vitamin deficiencies |
| Detoxification | Drink ≥2 L water/dayEat cruciferous vegetables to support liver enzymesLimit exposure to toxins (alcohol, smoking, BPA) |
What to Avoid
| Substance / Habit | Reason to Avoid | Spacing Tip |
|---|---|---|
| High-dose TMG (>3 g/day) | May increase LDL cholesterol in some individuals when used in excess | Stick to ≤2.5 g/day unless under medical supervision |
| Folate deficiency (no 5-MTHF) | Without adequate folate, TMG may not fully convert homocysteine to methionine | Ensure folate intake (400 mcg/day of methylfolate preferred) |
| Uncorrected B12 deficiency | TMG may worsen symptoms if B12 is low, as methylation demand increases | Always take with B12 (≥250–500 mcg/day) |
| Taking on Empty Stomach (Sensitive Users) | May cause mild nausea in some individuals | Take with food to improve absorption and reduce GI irritation |
| Alcohol & Smoking | Impairs methylation and depletes B-vitamin levels, negating TMG/B12 benefits | Limit alcohol; avoid smoking for optimal methylation health |
Third Party NABL Lab Report
Third Party NABL Lab Report for TMG trimethylglycine with Vitamin B12 :
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Frequently Asked Questions
What is HealthyHey TMG Trimethylglycine with Vitamin B12 and what are its key benefits?
HealthyHey TMG Trimethylglycine with Vitamin B12 is a premium-quality supplement designed to support overall wellness. It is manufactured in FSSAI-licensed, GMP-certified (audited by TÜV India), and FSSC 22000-certified facilities. Every batch is third-party tested at NABL-accredited labs for purity and potency.
How should I take HealthyHey TMG Trimethylglycine with Vitamin B12?
Take one to two capsules daily with a meal and a glass of water for optimal absorption, or as directed by your healthcare provider.
Are there any side effects of TMG Trimethylglycine with Vitamin B12?
HealthyHey TMG Trimethylglycine with Vitamin B12 uses well-studied ingredients at recommended dosages and is generally well-tolerated. Some individuals may experience mild digestive adjustment during the first few days. If you experience any adverse effects, discontinue use and consult your healthcare provider. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is HealthyHey TMG Trimethylglycine with Vitamin B12 vegetarian?
Please check the product label for dietary information. Most HealthyHey supplements use plant-based HPMC vegetarian capsules. The label clearly states whether the product is vegetarian or non-vegetarian.
What quality certifications does this product have?
HealthyHey TMG Trimethylglycine with Vitamin B12 is manufactured at facilities holding FSSAI licence, GMP certification (audited by TÜV India), FSSC 22000 V6, and ISO 22000 certifications. Each batch undergoes third-party testing at NABL-accredited laboratories, and we publish lab reports for transparency. Over 200 NABL lab reports have been published across our product range.
Can I take TMG Trimethylglycine with Vitamin B12 with other supplements?
Many supplements can be taken together safely. However, individual combinations depend on your health goals and existing medications. We recommend consulting your healthcare provider before combining multiple supplements, especially if you are pregnant, breastfeeding, or on prescription medication. Check our Recommended Stacks on healthyhey.com for clinically guided combinations.